Pterostilbene

What is Pterostilbene?

Pterostilbene is a naturally occurring polyphenol belonging to the stilbene family of plant compounds. It is structurally related to resveratrol but has two methoxy groups that make it significantly more stable and more easily absorbed by the body. This polyphenol is found in small amounts in plants such as in blueberries, grapes, almonds and certain tree barks, where it functions as a protective compound against environmental stress. Pterostilbene is most well known for its antioxidant and anti-inflammatory properties, which make it highly valuable for supporting various aspects of health.

Health Benefits:

Potent Antioxidant Action

The impressive antioxidant abilities of pterostilbene are well recognised and significantly contribute to protecting long term health. Pterostilbene helps to neutralise free radicals, limiting cellular and DNA damage, as well as preventing oxidative stress. This is key as oxidative stress has strong associations with aging and the development of various chronic diseases.

Supports Cardiovascular Health

Poor cardiovascular health and the development of cardiovascular diseases is linked to oxidative stress and inflammation, and therefore through its antioxidant and anti-inflammatory effects pterostilbene can support cardiovascular health. One study found that treatment with pterostilbene can protect against myocardial ischemia and reperfusion through its antioxidant effects and can also reduce inflammatory responses to myocardial ischemia and reperfusion. Another study evidenced that pterostilbene may decrease pathological cardiac remodelling and lower risk of heart failure.

Contributes to Cognitive Health

Pterostilbene may contribute to the maintenance of cognitive health in various ways including facilitating the regulation of neuronal signalling cascades, supporting synaptic plasticity, and aiding mitochondrial functionality. Studies indicate that pterostilbene may effectively limit age-linked cognitive decline, and could ameliorate neurodegenerative diseases such as Alzheimer's disease. Moreover, pterostilbene can effectively cross the blood-brain barrier allowing it to directly support brain health and function, and adding to its potential value for safeguarding neural health.

History:

Historically, pterostilbene was unknowingly used to support health through the consumption of blueberries which have long been valued in both European and Asian herbal traditions to reduce inflammation and improve circulation, digestion and general wellbeing. Modern research has since isolated pterostilbene as one of the compounds responsible for these benefits provided by blueberries, leading to its development as a concentrated nutritional supplement ingredient.

Typical Use:

Pterostilbene is typically used as an ingredient within supplements, particularly within products formulated to support antioxidant activity, longevity, cognition, and cardiovascular health. It is often combined with other beneficial ingredients such as resveratrol and quercetin to enhance its effects.