Protease

What is Protease?

Protease is a digestive enzyme that breaks down dietary protein into smaller peptides and individual amino acids. These amino acids are then absorbed and used by the body for tissue repair, immune function, enzyme production, and hormone synthesis. Protease is naturally produced in the stomach, pancreas, and small intestine, but supplemental protease is often used to support optimal digestion, particularly when protein intake is high or digestive function is compromised.

Health Benefits:

Supports Digestive Health

The most highly recognised function of protease is its role in breaking down dietary protein into amino acids and small peptides allowing for their absorption. Contributing to the effective absorption of amino acids is important as these serve as the building blocks for the synthesis of proteins, meaning they are implicated in muscle health, the production of hormones, immune function, and overall vitality.

Numerous studies have found that supplementing proteases can also improve gut microbiome composition in animals. Proteases are also suggested to enhance intestinal growth (villus height), support intestinal barrier function and have anti-inflammatory effects which could help relieve digestive discomfort and bloating linked to inflammatory conditions.

Assists Muscle Recovery and Repair

Amino acids released by protease activity are vital for muscle tissue growth, repair and maintenance, which is particularly important for highly active individuals and older adults. One study showed that protease supplementation can reduce muscle strength losses after eccentric exercise, and a further study evidenced that protease supplementation was associated with enhanced recovery of contractile function and reduced muscle soreness following downhill running.

Typical Use:

Protease is commonly taken in the form of supplements, with it often being incorporated into digestive enzyme blends or protein support formulas. Such supplements are most typically use by individuals recovering from illness, injury or intense physical activity. Protease may also be included in supplement formulations designed to support immune balance and inflammation control.