Lactobacillus salivarius

Abbi Neale | Published 20 February 2026

What is Lactobacillus salivarius?

Lactobacillus salivarius (L. salivarius) is a species of lactic acid producing bacteria naturally found in the human gastrointestinal tract, oral cavity and vaginal microbiota. It is classified as a probiotic microorganism, meaning that when administered in adequate amounts it is beneficial to health. This species of bacteria is capable of surviving passage through the digestive tract and certain strains have demonstrated the ability to adhere to intestinal epithelial cells and compete with undesirable bacteria.

Health Benefits:

Supports Digestive Health

L. salivarius can support digestive health through its ability to enhance gut microbiome diversity and reduce the growth of pathogens through the production of lactic acid, which lowers the pH level of the gut making it an unsuitable environment for them. This beneficial bacteria has also been shown to support the intestinal barrier by increasing tight junction proteins, which are key to gut barrier integrity and help to prevent a 'leaky gut'. Furthering this, studies show that L. salivarius may heighten goblet cell count and increase levels of Mucin 2, a gel-forming glycoprotein that creates the main protective mucus barrier in the intestines responsible for acting as a physical shield against pathogens and toxins.

May Modulate Immune System

Research has shown that this bacteria may contribute to immune system function and therefore support the maintenance of long term health. One study found that intragastric administration of both L. salivarius and Lactobacillus plantarum beneficially contributed to the immune response of mice, with greater expression of T helper 1 cells and various cytokines, increased phagocytosis, heightened macrophage energy metabolism and increased secretion of immunoglobulin A. Additionally, L. salivarius strains can produce several antimicrobial active compounds that exhibit antagonistic activity against pathogenic organisms, competing with pathogenic bacteria and damaging their cell walls and membranes. This anti-microbial effect works alongside the immune system to help prevent infections.

Could Support Women's Health

L. salivarius may contribute to the maintenance of a healthy vaginal microbiota by producing lactic acid which lowers pH, and producing bacteriocins that inhibit the growth of pathogens such as Candida albicans (linked to yeast infections), and Gardnerella vaginalis (linked to bacterial vaginosis). Additionally, emerging research indicates that L. salivarius may have beneficial effects on fertility and reproductive outcomes. For instance, one study found that the consumption of the CECT 30632 strain of L. salivarius led to improvements in pregnancy rates in women with habitual abortions and infertility of unknown origins.

Typical Use:

L. salivarius is commonly used as an ingredient within multi-strain probiotic capsules and powders to support digestive health and immune system support. L. salivarus is also sometimes included within women's microbiome support formulations to enhance female intimate health. This probiotic is also often used as a starter culture within functional foods such as cheese and yogurt to improve texture and provide probiotic health benefits.