What is Calcium Alpha Ketoglutarate?
Calcium Alpha Ketoglutarate (Ca-AKG) is a naturally occurring substance found within the body, and is a more stable, slow-release, and bioavailable form of AKG (Alpha-Ketoglutarate). Ca-AKG plays a central role in the production of cellular energy and can support various aspects of health including bone and muscle function.
Health Benefits:
Supports Longevity
Research suggests that Ca-AKG may provide powerful longevity boosting effects, indicating its value for extending lifespan and health span. One study found that oral supplementation with Ca-AKG led to increased survival, reduced morbidity and delayed onset of aging phenotypes in mice.
Enhances Muscle Performance
Ca-AKG may enhance muscle performance and recovery through its roles in protein synthesis, enhancing the production of ATP and supporting blood flow. One study found that AKG supplementation led to increased maximum power output and greater exercise tolerance and training effects in untrained men. In addition to this, studies suggest that treatment with AKG can support skeletal muscle regeneration in mice following injury and indicates that Ca-AKG may also be involved in regulating skeletal muscle atrophy.
Supports Bone Health
Ca-AKG shows potential for use to support bone health by boosting bone density and contributing to healthy bone formation and growth. One study found that AKG reduced age-related osteoporosis in mice, with the results showing increased bone mass and accelerated bone regeneration, alongside protection from bone loss.
Typical Use:
Ca-AKG is most commonly used in the form of capsule or powder form supplements aimed at supporting longevity and metabolic health due to its various beneficial effects. Within such supplements Ca-AKG can either be used on its own or as part of a formula in combination with complementary nutrients.
Sources:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8191137/
https://pmc.ncbi.nlm.nih.gov/articles/PMC11597751/
