What is D-Chiro Inositol?
D-chiro inositol is a naturally occurring isomer of inositol, a sugar compound that plays a key role in insulin signal transduction and glucose metabolism. D-chiro inositol can be produced in the body from the more abundant myo inositol, however in certain metabolic conditions this conversion is impaired, leading to reduced D-chiro inositol availability.
Health Benefits:
Aids Blood Sugar Regulation
Research has repeatedly shown that D-Chiro Inositol can aid healthy blood sugar regulation and this has been linked to its ability to support normal insulin sensitivity. One study found that following 3 months of treatment with myo inositol and D-chiro inositol there were significant decreases in fasting blood glucose levels.
Balances Hormones
D-chiro inositol may also contribute to hormonal balance, particularly for hormones crucial for healthy ovulation. This effect may occur through its improvements to insulin sensitivity and ability to reduce androgens. By supporting the healthy balance of hormones, D-chiro inositol may support mood regulation, reduce acne and limit weight gain.
Supports Reproductive and Ovarian Health
D-chiro inositol is well recognised for its ability to support reproductive and ovarian health. Supplements containing this ingredient are often used to relieve symptoms of PCOS such as irregular menstrual cycles, heightened levels of androgens and excess hair growth. Studies suggest that D-chiro inositol may also improve fertility by promoting regular ovulation, further evidencing the role of D-chiro inositol in supporting reproductive health.
Typical Use:
D-chiro Inositol is typically used in the form of supplements, often alongside myo inositol to support reproductive and hormonal health. D-chiro Inositol can also be consumed through various plant based foods including lentils, beans, citrus, peanuts and buckwheat.
Sources:
https://pmc.ncbi.nlm.nih.gov/articles/PMC5078644/
https://onlinelibrary.wiley.com/doi/10.1155/2018/1968450
https://pubmed.ncbi.nlm.nih.gov/38295772/
https://www.tandfonline.com/doi/full/10.1080/09513590.2023.2301554
