Cognitive Enhancers Cognitive enhancers, commonly known as ‘Nootropics’ refers to supplements and drugs that have a beneficial effect on brain function. The popularity of cognitive enhancers has surged in recent times, perhaps due in-part to Hollywood blockbuster Limitless. While cognitive enhancers cannot offer the the superhuman effects experienced by Bradley Cooper from NZT-48, they can significantly improve various aspects of cognitive health, including executive functions (e.g. concentration, attention, alertness, etc), memory, learning and motivation. .